Downside to Chelation Therapy

By DATUK DR ABDUL HAMID ABDUL KADIR

TO understand the background to the debate on complementary and

alternative treatments, one has to look at the Medical Act 1971.

Section 34(1) of the Act, in the sub-section “Malay, Chinese, Indian or

other native methods of therapeutics”, states:

“Subject to the provisions of sub-section (2) and regulations made

under this Act, nothing in this Act shall be deemed to affect the right

of any person – not being a person taking or using any name, title,

addition or description calculated to induce any person to believe that

he is qualified to practise medicine or surgery according to modern

scientific methods – to practise systems of therapeutics according to

purely Malay, Chinese, Indian or other native methods, and to demand and

recover reasonable charges in respect of such practice.”

The Act does not restrict any person from practising

native/traditional/complementary medicine, so long as the person is not a

medical practitioner registered under the provisions of the Medical Act

1971.

Whether complementary and/or traditional medicine is included by

definition in the “system of therapeutics according to purely Malay,

Chinese, Indian or other native methods” is open to interpretation.

However, it is common knowledge that those practising non- Western

complementary system of therapeutics normally use herbs and additionally

some allopathic medications.

The use of allopathic medications by such practitioners is, in most

instances, for diseases and indications not usually or conventionally

employed in the practice of evidence-based medicine.

Some clarifications on chelation therapy: It is a series of intravenous

infusions containing EDTA (disodium ethylene-diamine-tetraacetic acid),

an organic chemical (amino acid), which may be used to treat iron- load

from multiple blood transfusions, lead poisoning and other heavy metal

poisoning.

EDTA, or its sodium salt, is a chelating agent, forming co- ordination

compounds with most metal ions, such as calcium, magnesium or copper. In

medical and laboratory practice, EDTA is used as an anti- coagulant

additive. When blood is taken for tests, EDTA is added to prevent the

blood sample from clotting, by scavenging the calcium from the sample.

After EDTA was found effective in chelating and removing toxic metals,

like lead, from the blood, some scientists postulated that hardened

arteries could be softened if the calcium in their walls was removed.

This formed the basis for claims that chelation therapy is effective

against atherosclerosis, coronary heart disease and peripheral vascular

disease.

Its supposed benefits include increased collateral blood circulation,

decreased blood viscosity, improved cell membrane function, decreased

arterial vasospasm, decreased free radical formation, inhibition of the

aging process, reversal of atherosclerosis, decrease in angina, reversal

of gangrene, improvement of skin colour and healing of diabetic ulcers.

It is claimed chelation is effective against arthritis, multiple

sclerosis, Parkinson’s disease, psoriasis, Alzheimer’s disease, and

problems with vision, hearing, smell, muscle co-ordination and sexual

potency.

These claims have never been tested by scientific methods or found

effective in the treatment of such a multitude of diseases.

There are instances to show that there indeed are early and late

complications with chelation therapy, like the heavy loss in the urine of

trace metals like zinc, which has an important role in strengthening the

body’s immune function. Loss of large amounts of calcium through

chelation is also believed to create loss of calcium from bones.

Registered medical practitioners, on the other hand, practise

evidence-based medicine. The system of treatment of their patients is

based on well-established and sound scientific studies and principles of

therapeutics, and their efficacy to control, treat or modify diseases.

The system of therapeutics so advocated can be and is being practised

safely universally with predictable results in the vast majority of

patients.

The medications used by allopathic doctors are very specific for

well-defined disease conditions, and the composition, use and adverse

reactions are monitored by authorities established for such specific

purposes. In Malaysia, we have the Drug Control Authority.

Chelation therapy with EDTA would come under the category of

complementary medicine because its widespread use by some registered

medical practitioners is not how it had been used originally on

evidence-based therapeutic criterion.

By prescribing various supplements like large amounts of Vitamin C and

several B vitamins during chelation therapy for treatment of diseases

where there has been no scientific evidence adduced for their

effectiveness and efficacy in such diseases, registered medical

practitioners are, in fact, practising complementary medicine.

The onus to prove that chelation therapy, and other similar

complementary me- dical practices, is a sound, repeatable system of

therapeutics rests heavily on the proponents of complementary medicine.

Anecdotal testimony from patients is not enough.

Medical practitioners who treat their patients with chelation therapy

would have to show scientific evidence that their patients have improved,

not in the short term but more importantly, in the long term.

They have to produce documented case reports with long-term follow-up,

and data from autopsies of former patients. Doctors practising chelation

therapy have published no such data.

The few well-designed studies that have addressed the efficacy of

chelation for atherosclerotic diseases have been carried out by medical

scientists in the US Food and Drug Administration, the American Heart

Association, American Medical Association, American College of Physicians

and the University of Calgary, to name a few. Without exception, these

studies found no evidence chelation worked. There are many patients in

Malaysia who claim to have benefited from chelation therapy and some have

written testimonials and have volunteered to give evidence in person.

Many others who have not benefited remain silent sufferers.

The Medical Act 1971 has no jurisdiction over non-registered or

non-medical persons who practise complementary medicine or native

medicine or traditional medicine. But registered medical practitioners

who practise such medicine would clearly be misleading the public; and

presenting themselves as trained, registered and certified to practise

all systems of therapeutics, thereby adding credibility to their

practice.

There may be a place in the future for “integrative medicine”, but let

us not ignore the fact that even in advanced countries where such

practice is finding a niche, there is widespread opposition which cannot

be dismissed simply as a professional turf war.

The Ministry of Health is “keeping an open mind” about the practice of

complementary and traditional medicine in Malaysia.

It is a fact that the ministry and the universities are looking into

ways and means of regulating traditional and herbal medicine practice by

analysing the hundreds of such medications being sold openly in this

country.

Members of the public have the right to choose whatever system of

treatment they prefer for whatever reason.

But it is also the mandated right of the ministry to set the standards

of health care, and to demonstrate its duty and responsibility to point

out to the public the various pitfalls in any system and the unpleasant

consequences.

DATUK DR ABDUL HAMID ABDUL KADIR

Ethics Committee chairman Malaysian Medical Council Ministry of Health